Chronic hepatitis C is a serious disease, but thanks to the achievements of modern medicine it can be overcome. This will help the drug Generic Harvoni, the inhibitory effect of the viral protein NS5A, which is responsible for the assembly, replication, and secretion of viral RNA.
Each tablet contains 90 mg of the active substance ledipasvir and 400 mg of sofosbuvir. Both of these components together actively resist the spread of the hepatitis C virus. HARVONI cannot be bought in a regular pharmacy since Indian generics are not licensed in Russia, but it can be ordered on the Internet with delivery from India
Indications for use
This medicine is suitable for adults with chronic hepatitis C and genotypes 1 and 4.
Fashion or application
The HARVONI package contains twenty-eight tablets, in each of which of the active substance - ledipasvir sofosbuvir price itself or the auxiliary component. It is necessary to take one tablet a day, swallow it whole and drink it with a glass of water. Grind or chew is prohibited. It's best to take medicine with meals. The duration of treatment and the necessary doses are set and adjusted by the doctor himself.
In parallel with ledipasvir, other drugs that contribute to the action of the active substance may be prescribed. The average course lasts, as a rule, from 12 to 24 weeks, which depends on the severity of the disease and the nature of the course. With the manifestation of mild side effects (1, 2 severity), the reception should not be interrupted. If the drug cause severe harm to the body or are ineffective, then the course should be interrupted.
According to the recommendations of EASL 2016 for patients with genotypes 1a and 1b, treatment should be completed within 8-12 weeks. For patients with genotype 4 - about - 12 weeks. The extension of treatment depends on the severity of the disease. During the use of Indian generics, ribavirin is often prescribed in parallel. In the presence of adverse reactions, ribovirin is removed from treatment, and Harvoni Cost continues for 24 weeks. A similar option is the same for all valid genotypes.
The stronger the medicine acts, the more it has side effects. HARVONI is no exception. In certain cases, taking it is not recommended or prohibited:
- During pregnancy, lactation. If you plan to conceive, be sure to inform your doctor.
- Taking prescription and over-the-counter products (nutritional supplements, herbal supplements).
- The presence of allergic reactions, even if they have not been manifested for a long time.
- Impaired kidney or liver function. With such irreversible reactions of the body (illness and allergies), the medicine can be replaced with a similar one containing only sofosbuvir.
- You should be extremely careful - there is no antidote to side effects, and side effects are eliminated symptomatically.
- Some medicines may not interact with HARVONI. They either reduce to zero its actions, or start to harm the body:
- Taking simeprevir in most cases increases the risk or side effects during treatment with ledipasvir.
- Carbamazepine, St. John's wort, phenobarbital, oxcarbazepine, rifampin, phenytoin, rifabutin, and rifapentin can lower the effectiveness of the drug.
- Digoxin or rosuvastatin intolerance may develop while taking the medicine.
- The effect of Ledipasvir on reproductive functions has not yet been established, therefore, adult girls and women should take the device with caution and monitor the body's reaction.
- During the course, girls need to carefully take care of contraception methods and avoid pregnancy at least another six weeks after taking it.
Keep the drug in a dry, preferably dark place. At temperatures up to 30 degrees. HARVONI you can buy or make a direct delivery order from India right now on our forum.
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